1,4-Butanediol CAS 110-63-4

1,4-butanediol (BD) is an industrial chemical, and is illicitly used as a substitute to gamma-hydroxybutyric acid (GHB). BD and gamma-butyrolactone (GBL) are structurally similar to GHB and there is a large body of evidence to confirm that GBL and BD are converted to GHB after oral administration.

BDO has similar pharmacological effects to GHB in part because it is readily converted into GHB by the body’s own natural process. GHB is present in the central nervous system in very small concentrations; it is a metabolite of the neurotransmitter gamma-aminobutyric acid (GABA). Scientific data suggest that GHB can function as a neurotransmitter or neuromodulator in the brain. It produces dose-dependent depressant effects similar to those of the barbiturates and methaqualone. Low doses of BD/GHB produce drowsiness, nausea, and visual distortion.

SKU: 110-63-4 Category:

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Product Information
CAS number110-63-4
EC number203-786-5
Hill FormulaC₄H₁₀O₂
Chemical formulaHO(CH₂)₄OH
Molar Mass90.12 g/mol
Structure formula Image
Application1,4-Butanediol for synthesis. CAS 110-63-4, chemical formula HO(CH₂)₄OH.
Physicochemical Information
Boiling point228 °C (1013 hPa)
Density1.02 g/cm3 (20 °C)
Explosion limit1.95 – 18.3 %(V)
Flash point134 °C
Ignition temperature385 °C
Melting Point16 °C
pH value7 – 8 (500 g/l, H₂O, 20 °C)
Vapor pressure<0.1 hPa (20 °C)
Viscosity kinematic83.2 mm2/s (20 °C)
Toxicological Information
LD 50 oralLD50 Rat 1525 mg/kg
LD 50 dermalLD50 Rabbit > 2000 mg/kg
Storage and Shipping Information
StorageStore below +30°C.
Assay (GC, area%)≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C)1.015 – 1.016
Water (K. F.)≤ 0.30 %
Identity (IR)passes test
Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.

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