Chemical Name | 3′-Methylpropiophenone |
CAS Number | 51772-30-6 |
Molecular Formula | C₁₀H₁₂O |
Appearance | Colourless Oil |
Molecular Weight | 148.2 |
Storage | 4°C, Inert atmosphere |
Solubility | Chloroform (Soluble), Methanol (Sparingly) |
Category | Building Blocks; Miscellaneous; |
Applications | 3′-METHYLPROPIOPHENONE (cas# 51772-30-6) is a useful research chemical. |
Description | 3-Methylpropiophenone (3-MPP) is an organic compound that is widely used in the scientific field due to its wide range of applications. It is a colorless, crystalline solid with a molecular weight of 164.2 g/mol and a melting point of 76°C. It is soluble in water and alcohol, and is readily available from commercial suppliers. 3-MPP is used as a starting material for the synthesis of various compounds and as a reagent in chemical reactions. It is also used in the production of various pharmaceuticals, agrochemicals, and fragrances. |
Synthesis Method | 3′-Methylpropiophenone is synthesized through a two-step reaction process. In the first step, a Grignard reagent is reacted with a carbonyl compound to form a ketone. In the second step, the ketone is reacted with a base to form 3′-Methylpropiophenone. The reaction is as follows: Reaction 1: R-MgBr + R’-CO → R’-CO-R + MgBr2 Reaction 2: R’-CO-R + OH- → R’-CO-OH + R- |
Scientific Research Applications | 3′-Methylpropiophenone is widely used in the scientific research field due to its wide range of applications. It has been used in the synthesis of various compounds, such as drugs, agrochemicals, and fragrances. It is also used in the production of polymers, polyesters, and polyurethanes. 3′-Methylpropiophenone has also been used in the synthesis of polymers for drug delivery systems. Additionally, it has been used in the synthesis of polymers for the immobilization of enzymes. |
Mechanism of Action | 3′-Methylpropiophenone acts as a catalyst in chemical reactions, promoting the formation of products from reactants. It acts as a nucleophile, attacking the electrophilic carbon of the carbonyl group. This reaction is followed by a proton transfer, which results in the formation of a new bond between the electron-rich carbon and the nucleophile. This reaction is known as nucleophilic addition. |
Biochemical and Physiological Effects | 3′-Methylpropiophenone is not known to have any adverse biochemical or physiological effects. It is not toxic and does not interact with other drugs or chemicals. It is not metabolized by the body, and is rapidly excreted in the urine. |
Advantages and Limitations for Lab Experiments | 3′-Methylpropiophenone is a versatile reagent that is widely used in the laboratory due to its ease of use and availability. It is relatively inexpensive and has a wide range of applications. However, it is not suitable for use in reactions that involve high temperatures or pressures, as it is volatile and can decompose at high temperatures. |
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