Flubromazolam CAS 612526-40-6

Description	Flubromazolam is a novel psychoactive substance (NPS) that has recently emerged on the research chemical market. It is a benzodiazepine derivative, and is similar in structure to other benzodiazepines such as alprazolam and diazepam. Flubromazolam has sedative, anxiolytic, and hypnotic properties, and is used in laboratory experiments to study the effects of benzodiazepines.
Synthesis Method	Flubromazolam is synthesized by the reaction of 2-bromo-4-chloro-5-methyl-1H-benzodiazepine with 2-chloro-5-methyl-1H-benzodiazepine in the presence of anhydrous potassium carbonate and dimethyl sulfoxide. The reaction is carried out at room temperature and the product is obtained in high yields.
Scientific Research Application	Flubromazolam has been used in scientific research to study the effects of benzodiazepines on the central nervous system. It has been used to study the effects of benzodiazepines on anxiety, sleep, memory, and cognition. It has also been used to study the effects of benzodiazepines on drug addiction and withdrawal.
Mechanism of Action	Flubromazolam acts by binding to the benzodiazepine receptor in the brain. This binding increases the activity of the neurotransmitter GABA, which is responsible for inhibiting the activity of neurons. This inhibition leads to the sedative, anxiolytic, and hypnotic effects of flubromazolam.
Biochemical and Physiological Effects	Flubromazolam has sedative, anxiolytic, and hypnotic effects. It has been shown to reduce anxiety, improve sleep, and improve memory and cognition. It has also been shown to reduce drug addiction and withdrawal symptoms.
Advantages and Limitations for Lab Experiments	The main advantage of using flubromazolam in laboratory experiments is its high potency and long duration of action. This makes it ideal for studying the effects of benzodiazepines on the central nervous system. The main limitation is that flubromazolam is not approved for human consumption, so it should only be used in laboratory experiments.
Future Directions	Future research on flubromazolam could focus on its effects on anxiety, sleep, memory, and cognition. It could also be used to study the effects of benzodiazepines on drug addiction and withdrawal. Additionally, further research could be conducted to examine the long-term effects of flubromazolam on the central nervous system. Finally, research could be conducted to evaluate the safety and efficacy of flubromazolam in humans.
CAS RN	612526-40-6
Product Name	Flubromazolam
Molecular Formula	C17H12BrFN4
Molecular Weight	371.2 g/mol
IUPAC Name	8-bromo-6-(2-fluorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
InChI	InChI=1S/C17H12BrFN4/c1-10-21-22-16-9-20-17(12-4-2-3-5-14(12)19)13-8-11(18)6-7-15(13)23(10)16/h2-8H,9H2,1H3
InChI Key	VXGSZBZQCBNUIP-UHFFFAOYSA-N
SMILES	CC1=NN=C2N1C3=C(C=C(C=C3)Br)C(=NC2)C4=CC=CC=C4F
Canonical SMILES	CC1=NN=C2N1C3=C(C=C(C=C3)Br)C(=NC2)C4=CC=CC=C4F
Other CAS RN	612526-40-6
Synonyms	8-bromo-6-(2-fluorophenyl)-1-methyl-4H-(1,2,4)triazolo(4,3-a)(1,4)benzodiazepine flubromazolam

Flubromazolam is a potent sedative-hypnotic benzodiazepine derivative. It is chemically related to the widely known benzodiazepine diazepam and shares similar pharmacological effects. Flubromazolam has a high affinity for the benzodiazepine receptor, which results in its strong sedative, anxiolytic (anti-anxiety), muscle relaxant, and amnesic properties.

Due to its potency, flubromazolam is typically used in research settings and is not approved for medical or therapeutic use. It is known for its long duration of action, with effects lasting up to several days. The compound is sold as a research chemical and is sometimes obtained illicitly for recreational use.

It is important to note that the use of flubromazolam and other benzodiazepines carries significant risks, particularly when used recreationally or without medical supervision. These risks include the potential for sedation, respiratory depression, amnesia, dependence, and addiction. Benzodiazepines should only be used under the guidance of a qualified healthcare professional and as prescribed.

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