- Olivetol, also known as 5-pentylresorcinol or 5-pentyl-1,3-benzenediol, is an organic compound found in certain species of lichen;
Chemical Name Olivetol Synonyms 3,5-Dihydroxyamylbenzene; 5-n-Amylresorcinol; 5-n-Pentylresorcinol; 1,3-Dihydroxy-5-pentylbenzene; 5-Pentyl-1,3-benzenediol; CAS Number 500-66-3 Molecular Formula C₁₁H₁₆O₂ Appearance Colourless to Beige Oil to Low-Melting Solid Melting Point 39 – 40°C Molecular Weight 180.25 Storage 4°C, Inert atmosphere, Light sensitive Solubility Chloroform (Slightly), Methanol (Slightly) Stability Light Sensitive Category Building Blocks; Miscellaneous; Applications Olivetol is a precursor in various syntheses of tetrahydrocannabinol.
Olivetol is a naturally occurring organic compound. It is found in certain species of lichens and can be readily extracted.[1
Synthesis of THC analogs
A method for the synthesis of THC itself consists of the condensation reaction between olivetol and Δ2-carene oxide.
The production, possession, and/or distribution of olivetol is not outlawed by any country; however, in the United States, it is a DEA watched precursor.
Olivetol is a chemical compound with the molecular formula C10H10O2. It is a naturally occurring organic compound that belongs to the class of phenols. Olivetol is commonly found in certain plants, such as lichens and liverworts.
One of the notable uses of olivetol is its role as a precursor in the synthesis of cannabinoids, which are a group of compounds found in cannabis plants. Olivetol serves as a building block for the formation of various cannabinoids, including cannabigerolic acid (CBGA), which is the precursor to many other cannabinoids like THC (tetrahydrocannabinol) and CBD (cannabidiol).
In the process of synthesizing cannabinoids, olivetol combines with another compound called geranyl pyrophosphate to produce CBGA. From CBGA, different enzymes and chemical reactions lead to the formation of different cannabinoids with various properties and effects.
It’s worth noting that olivetol itself does not possess significant pharmacological activity or psychoactive effects. Its importance lies in its role as a precursor molecule in the biosynthesis of cannabinoids, which are the active compounds responsible for the effects of cannabis.
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