Olivetol 500-66-3

What is the biological activity of Olivetol?

Olivetol is a naturally occurring organic compound. It is present in certain lichen species and can be easily extracted. It is also produced by many insects as a pheromone, insect repellent or antiseptic.Some people using it to make Cannabichromene.

As expected, olivetol showed antioxidant and anticholinergic properties.

Satisfied with the product. Cannabinoids are synthesized via pyridine-catalysed citral-olivetol condensation.

Olivetol, also known as 5-pentylresorcinol or 5-pentyl-1,3-benzenediol, is an organic compound found in certain species of lichen;

It is also a precursor in various syntheses of tetrahydrocannabinol.

Chemical NameOlivetol
Synonyms3,5-Dihydroxyamylbenzene; 5-n-Amylresorcinol; 5-n-Pentylresorcinol;
1,3-Dihydroxy-5-pentylbenzene; 5-Pentyl-1,3-benzenediol;
CAS Number500-66-3
Molecular FormulaC₁₁H₁₆O₂
AppearanceColourless to Beige Oil to Low-Melting Solid
Melting Point39 – 40°C
Molecular Weight180.25
Storage4°C, Inert atmosphere, Light sensitive
SolubilityChloroform (Slightly), Methanol (Slightly)
StabilityLight Sensitive
CategoryBuilding Blocks; Miscellaneous;
ApplicationsOlivetol is a precursor in various syntheses of tetrahydrocannabinol.


Olivetol is a naturally occurring organic compound. It is found in certain species of lichens and can be readily extracted.[1

Olivetol is also produced by a number of insects, either as a pheromone, repellent, or antiseptic.[2][3]

The cannabis plant internally produces the related substance olivetolic acid (OLA), which may be involved in the biosynthesis of tetrahydrocannabinol (THC).[4][5]

Synthesis of THC analogs

Olivetol is used in various methods to produce synthetic analogs of THC. One such method is a condensation reaction of olivetol and pulegone.In PiHKAL,

Alexander Shulgin reports a cruder method of producing the same product by bringing to reaction olivetol and the essential oil of orange in the presence of phosphoryl chloride.[7]

A method for the synthesis of THC itself consists of the condensation reaction between olivetol and Δ2-carene oxide.[8]


The production, possession, and/or distribution of olivetol is not outlawed by any country; however, in the United States, it is a DEA watched precursor.[9]

Olivetol is a chemical compound with the molecular formula C10H10O2. It is a naturally occurring organic compound that belongs to the class of phenols. Olivetol is commonly found in certain plants, such as lichens and liverworts.

One of the notable uses of olivetol is its role as a precursor in the synthesis of cannabinoids, which are a group of compounds found in cannabis plants. Olivetol serves as a building block for the formation of various cannabinoids, including cannabigerolic acid (CBGA), which is the precursor to many other cannabinoids like THC (tetrahydrocannabinol) and CBD (cannabidiol).

In the process of synthesizing cannabinoids, olivetol combines with another compound called geranyl pyrophosphate to produce CBGA. From CBGA, different enzymes and chemical reactions lead to the formation of different cannabinoids with various properties and effects.

It’s worth noting that olivetol itself does not possess significant pharmacological activity or psychoactive effects. Its importance lies in its role as a precursor molecule in the biosynthesis of cannabinoids, which are the active compounds responsible for the effects of cannabis.


Top selling raw materials



PMK POWDER 28578-16-7

BMK POWDER 5449-12-7

(2-Chlorophenyl) -2-Nitrocyclohexanone   CAS 2079878-75-2

N-phenylpiperidin-4-amine CAS 23056-29-3

Bromazolam CAS 71368-80-4

Metonitazene Cas 14680-51-4

Dipyanone  CAS 60996-94-3

Etadesnitazene CAS 911-65-9

71368-80-4  Bromazolam

Protonitazene (hydrochloride)  CAS 119276-01-6

5337-93-9 4-Methylpropiophenone

1451-82-7 2-bromo-4-methylpropiophenone

1009-14-9     Valerophenone

925-90-6     Ethylmagnesium Bromide

86-29-3     Diphenylacetonitrile

49851-31-2 2-BROMO-1-PHENYL-PENTAN-1-ONE

124878-55-3 2-iodo-1-phenylpentan-1-one

2079878-75-2 2-(2-Chlorophenyl)-2-nitrocyclohexanone

6303-21-5 Hypophosphorous acid



There are no reviews yet.

Be the first to review “Olivetol 500-66-3”

Your email address will not be published. Required fields are marked *