Name | Vardenafil hydrochloride trihydrate |
CAS | 224785-90-4 |
EINECS(EC#) | 200-835-2 |
Molecular Formula | C23H39ClN6O7S |
MDL Number | MFCD08458876 |
Molecular Weight | 579.11 |
MOL File | 224785-90-4.mol |
What is Vardenafil used for?
Vardenafil is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Vardenafil is in a class of medications called phosphodiesterase (PDE) inhibitors. It works by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Vardenafil does not cure erectile dysfunction or increase sexual desire. Vardenafil does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV).
Vardenafil is a medication that is primarily used to treat erectile dysfunction (ED) in men. It belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. Vardenafil helps to increase blood flow to the penis, which leads to improved erectile function.
When a man is sexually stimulated, the release of nitric oxide (NO) in the penile tissues activates an enzyme called guanylate cyclase. This enzyme increases the levels of cyclic guanosine monophosphate (cGMP), which relaxes the smooth muscles in the blood vessels of the penis, allowing for increased blood flow and the achievement and maintenance of an erection.
However, an enzyme called phosphodiesterase type 5 (PDE5) breaks down cGMP, resulting in decreased blood flow and difficulty in achieving or maintaining an erection. Vardenafil inhibits the action of PDE5, leading to increased levels of cGMP and improved blood flow, thus facilitating erectile function.
Vardenafil is available in tablet form and is usually taken orally prior to sexual activity. The exact dosage and timing should be determined by a healthcare professional based on individual needs and response to the medication. It is important to follow the prescribed instructions and not exceed the recommended dose.
Like any medication, vardenafil can have side effects. Common side effects may include headache, dizziness, flushing, nasal congestion, indigestion, and back pain. Rare but more serious side effects include changes in vision or hearing, prolonged or painful erections (priapism), and allergic reactions. If any concerning side effects occur, it is important to seek medical attention.
Vardenafil should not be taken by individuals who are also using nitrates or nitric oxide donors, as the combination can cause a sudden and significant drop in blood pressure. It is also important to disclose all other medications being taken to a healthcare professional, as certain drugs may interact with vardenafil.
It is crucial to consult with a healthcare professional before starting vardenafil or any other medication for erectile dysfunction to ensure it is safe and appropriate for an individual’s specific health situation.
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