PMK Glycide powder oil is an analytical reference standard categorized as a precursor in the synthesis of methylenedioxy phenethylamines and amphetamines, including 3,4-MDMA.
Is PMK ethyl glycinate the same as PMK methyl glycinate?
PMK ethyl glycinate (Cas 28578-16-7) is an analytical reference standard categorized as a precursor in the synthesis of methylenedioxy phenethylamines and amphetamines, including 3,4-MDMA. This product is intended for research and forensic applications.
There are two specifications: PMK methyl Glycidate powder Cas 13605-48-6, PMK ethyl Glycidate oil Cas 28578-16-7.
Most routers for the synthesis of 3,4-methylenedioxymethamphetamine (MDMA) start from compounds containing 3,4-methylenedioxyphenyl rings, such as safrole, isosafrole, piperonal, Bromo safrole, and piperonal methyl ketone (piperonal methyl ketone, PMK), etc.PMK is currently the most important precursor compound for the synthesis of MDMA in underground processing plants, and MDMA can be prepared by the simple Lukat method or reductive amination method.
Since 2010, some underground processing plants of MDMA have gradually discovered that a PMK derivative, PMK methyl glycidate, is used to produce PMK , and then MDMA is produced
The structural formula of PMK methyl glycate
H-NMR and 13 C-NMR spectra (Figures 3~4) of the samples were assigned, and each signal was consistent with the structure of PMK methyl glycinate . The group peaks are the signal after the benzene ring is substituted by the 1, 3, and 4 positions; δ 6.04 is a single, which is the methylene signal directly connected to two oxygen atoms; two singlets of δ 4.28 and δ 3.73 are the connection, respectively The methine and methyl signals of the oxygen atom;
the single peak of δ 1.24 is the methyl signal connected to the tertiary carbon; the four signals in the high-field region of the carbon spectrum are the primary carbon, the primary carbon connected to an oxygen atom, and the tertiary carbon. and quaternary carbon signals; δ 101.67 is the secondary carbon signal connecting two oxygen atoms; the six signals of δ 107.44~147.77 are the signals of six carbon atoms on the benzene ring; δ 170.96 is the carbonyl carbon signal of methyl ester.
H NMR spectrum of the sample PMK Glycidate
C NMR spectrum of the sample PMK Glycidate
CAS 28578-16-7 Pmk oil 85% high yield PMK Glycide liquid when you storage in room temperature
This paper reports for the first time a case of PMK methyl glycidate (also known as MDP2P methyl glycidate) detected in mainland China, which was analyzed by gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) techniques.
References
| [1] | CASON T A D. An evaluation of the potential for cland estine manufacture of 3, 4-methylenedioxyamphetamine (MDA) analogs and homologs[J]. Journal of Forensic Sciences, 1990, 35(3): 675-697. |
| [2] | SCHÄFFER M, DIECKMANN S, PÜTZ M, et al. Impact of reaction parameters on the chemical profile of 3, 4-methylenedioxymethamphetamine synthesized via reductive amination: Target analysis based on GC-qMS compared to non-targeted analysis based on GC × GC-TOF-MS[J]. Forensic Science International, 2013, 233(1-3): 201-211. |
| [3] | United Nations Office on Drugs and Crime. World drug report 2017[R]. United Nations Publication, 2017. |
| [4] | Designation of 3, 4-MDP-2-P Methyl Glycidate (PMK Glycidate), 3, 4-MDP-2-P Methyl Glycidic Acid (PMK Glycidic Acid), and Alpha-Phenylacetoacetamide (APAA) as List I Chemicals [Z/OL]. [2021-01-03]. https://www.deadiversion.usdoj.gov/fed_regs/rules/2020/fr1221.htm. |
